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Mean
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(Minimum/maximum)
|
|---|
|
Age (years)
|
43 ± 0.45
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(18–74)
|
|
Weight (kg)
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110.7 ± 0.8
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(65.8–226.6)
|
|
Height (m)
|
1.68 ± 0.003
|
(1.47–2.06)
|
|
BMI (kg/m2)
|
38.8 ± 0.22
|
(24.97–69.13)
|
|
Waist circumference (cm)
|
116.7 ± 0.5
|
(83.5–193)
|
|
Hip circumference (cm)
|
122.2 ± 0.4
|
(95–160)
|
|
Waist-to-hip ratio
|
0.96 ± 0.004
|
(0.66–1.35)
|
|
Fat free mass (kg)
|
56.2 ± 0.4
|
(36.5–110)
|
|
Fat mass (kg)
|
54.3 ± 0.5
|
(16.9–134.5)
|
|
Fat mass (%)
|
48.87 ± 0.27
|
(22.3–65.3)
|
|
Total abdominal adipose tissue (cm2)
|
799.5 ± 6.6
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(246–1386)
|
|
Visceral abdominal tissue (cm2)
|
195.9 ± 3.2
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(29–567)
|
|
Subcutaneous abdominal tissue (cm2)
|
603.6 ± 5.6
|
(166–1059)
|
|
Systolic blood pressure (mmHg)
|
127.1 ± 0.5
|
(90–180)
|
|
Diastolic blood pressure (mmHg)
|
75.45 ± 0.37
|
(49–115)
|
|
Creatinine kinase (mg/dL)
|
0.81 ± 0.006
|
(0.38–1.64)
|
|
Aspartate aminotransferase (U/L)
|
23.6 ± 0.5
|
(7–133)
|
|
Alanine aminotransferase (U/L)
|
35.8 ± 0.8
|
(7–265)
|
|
Alkaline phosphatase (U/L)
|
79.94 ± 0.79
|
(30–236.03)
|
|
gamma-glutamyltransferase (U/L)
|
43.43 ± 1.19
|
(11.79–315.16)
|
|
Total cholesterol (mg/dL)
|
199 ± 1.40
|
(75–400.44)
|
|
High-density-lipoprotein Cholesterol (mg/dL)
|
50.83 ± 0.49
|
(24–107.17)
|
|
Triglycerides (mg/dL)
|
152.97 ± 2.93
|
(17–823.01)
|
|
Low-density-lipoprotein cholesterol (mg/dL)
|
117.81 ± 1.24
|
(17.6–294.76)
|
|
Insulin resistance (HOMA)
|
4.27 ± 0.23
|
(0.07–147.65)
|
|
Steatosis (0:1:2:3)
|
109:151:119:82
| |
|
Ballooning (0:1:2)
|
139:187:135
| |
|
Lobular inflammation (0:1:2:3)
|
148:208:75:30
| |
|
Fibrosis stage (0:1:2:3:4)
|
287:91:51:28:3
| |
|
Adjusted SAF activity (0:1:2:3:4:5)
|
100:71:112:118:44:16
| |
|
NAFLD activity score (0:1:2:3:4:5:6:7:8)
|
75:44:48:62:84:60:50:30:8
| |
|
NAFLD staging (1:2:3:4)
|
61:80:210:53
| |
- Patient clinical and biochemical variable statistics are represented for the complete HEPADIP cohort (Ntotal = 790; 565 females—225 males). Values are expressed as the mean ± standard error of the mean. Lower and upper limits are indicated as minimum/maximum. The distribution of patients (x:y:z) according to the histological characteristics (Nliver biopsy = 461) are shown as absolute values. The histological criteria were evaluated by the NASH-CRN scoring system
