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Table 3 Correlation between CBP and GCN5 expression and the status of ER, PR, HER2 and ki-67 in tissue samples from breast cancer patients

From: The impact of CBP expression in estrogen receptor-positive breast cancer

Molecular subtypes Total No. of missing data (%) CBP expression Total No. of missing data (%) GCN5 expression
Negative (%)a Positive (%)b p valuec Negative (%)a Positive (%)b p valuec
ER status
Negative 75   17 (22.7) 58 (77.3) 0.0001 78   14 (17.9) 64 (82.1) 0.213
Positive 124   6 (4.8) 118 (95.2)   123   14 (11.4) 109 (88.6)  
Total 199 10 (4.8)     201 10 (4.7)    
PR status
Negative 71   17 (23.9) 54 (76.1) 0.0001 74   13 (17.6) 61 (82.4) 0.541
Positive 125   7 (5.6) 118 (94.4)   123   17 (13.8) 106 (86.2)  
Total 196 13 (6.2)     197 14 (6.6)    
HER2
Negative 180   22 (12.2) 158 (87.8) 1.000 181   26 (14.4) 155 (85.6) 0.552
Positive (> 30%) 21   3 (14.3) 18 (85.7)   22   2 (9.1) 20 (90.9)  
Total 201 8 (3.8)     203 8 (3.8)    
Ki-67 status
≤ 20% 183   22 (12.0) 161 (88.0) 0.354 184   30 (16.3) 154 (83.7) 0.094
> 20% 24   4 (16.7) 20 (83.3)   24   1 (4.2) 23 (95.8)  
Total 207 2 (1.0)     208 3 (1.4)    
  1. aNegative: IRS 0 to 5
  2. bPositive: IRS 6 to 9
  3. cChi-square test
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